Primary cells are booming on account of the escalating demand for monoclonal antibodies and the growing focus on personalized medicine. Primary cells are separated from human or animal tissue via enzymatic or mechanical methods. This cell is placed in an artificial environment in glass or plastic containers for support with a specialized medium containing essential nutrients and growth factors to support proliferation. The primary cell also provides a model system for study and research on normal physiology and biochemistry of cells (like metabolic studies, aging, signaling studies) and the effects of drugs and toxic compounds on the cells. The primary cell is widely used in life science research companies and research institutes. The Global Primary Cells Market is estimated to see healthy growth, pegged at a CAGR of around 10.8% throughout the forecast period 2020-2025.
Cancer is a leading cause of death across the globe. Primary cell plays a vital role in cancer diagnostic research. Primary cells are ideal models for cancer biomarker discovery and drug screening. Further, these cells are used to understand the biochemical pathways of cellular interactions. In cancer research, primary cells are exposed to heavy radiation doses, viruses, and chemicals, which transform these cells into cancer cells via genetic mutations and the introduction of oncogenes. In this way, study and research are done on the molecular-level mechanism and cause of cancer and the altered signaling pathways of cancerous cells.
With the advent of 3D cultures, primary cells are considered more biologically representative compared to cell lines. This is due to their very identical characteristics to the original donor tissue and can produce biologically representative models of in vivo multicellular environment. For instance: primary hepatocytes cells can be undifferentiated and die within four days when cultured as a monolayer on plastic. The primary cells provide consistent tissue-specific responses in a biologically relevant microenvironment and do not give any incorrect responses in a cellular context. This further helps in decreasing the expenditure on animal models required for in vivo studies and is cost-effective. Thus, various biological and pharmaceutical companies and CROs are adopting primary cells for their drug discovery process.
Additionally, with the innovation of genetic engineering, there has been a significant increase in the use of biopharmaceutical products, including monoclonal antibodies and recombinant proteins. The production is greatly dependent on protein expression systems derived from mammalian primary cultures. These cultures are being used to study cancer mechanisms and develop treatment therapies.
Segmentation Overview of the Global Primary Cells Market
The primary cells market is segmented into the origin, type, and end use. These major market segments are further categorized into various sub-segments to study the market in detail.
By Origin Outlook (Human Primary Cells and Animal Primary Cells)
By Type Outlook (Hematopoietic Cells, Dermatocytes, Gastrointestinal Cells, Hepatocytes, Lung Cells, Renal Cells, Heart Cells, Musculoskeletal Cells, and Other Primary Cells)
By End Use Outlook (Life Science Research Companies and Research Institutes)
Key Players Insights
Thermo Fisher Scientific, Inc., Merck Kgaa, Lonza, Promocell Gmbh, Corning Incorporated, American Type Culture Collection (ATCC), Biologics, Inc., Hemacare Corporation (A Charles River Laboratories, Inc. Company), Zenbio, Inc., Stem Cell Technologies, Inc., Allcells, among others, are some key market players included in the research study of the global primary cells market.
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